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Smurf1-IN-A01
Item number: TGM-T16904-100mg
Description: Smurf1-IN-A01 (A01) is a ubiquitin ligase Smad ubiquitination regulatory factor-1 inhibitor (Kd: 3.664 nM) that enhances BMP-2 responsiveness by preventing Smurf1-mediated Smad1/5 degradation. Target: Others. Smiles: Cc1ccnn1-c1ccc(cc1)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F. References: Cao Y,...
| Keywords: | A01 |
| Application: | Smurf1 inhibitor |
| CAS | 1007647-73-5 |
| MW: | 512.93 D |
From 33.00€
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A01
Item number: Cay26137-10
A01 is an inhibitor of Smad ubiquitination regulatory factor 1 (Smurf1) ubiquitin ligase (Kd = 3.67 nM). It inhibits Smurf1-mediated ubiquitination of Smad1/5 and increases Smad1/5 protein levels in C2C12 cells stimulated with bone morphogenic protein 2 (BMP2) in a concentration-dependent manner. A01 (2 µM)...
| Keywords: | [4-[[4-chloro-3-(trifluoromethyl)phenyl]sulfonyl]-1-piperazinyl][4-(5-methyl-1H-pyrazol-1-yl)phenyl]-methanone |
| Application: | Smurf1 inhibitor |
| CAS | 1007647-73-5 |
| MW: | 512.9 D |
From 133.00€
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