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Lipid-based Drug Delivery Tools
Sphingosine-1-phosphate (d18:1)
Item number: Cay62570-1
Sphingosine-1-phosphate (S1P) is the product of phosphorylation of sphingosine by sphingosine kinase that is secreted from cells and acts as an agonist at S1P receptors. It increases intracellular calcium levels in TAg-Jurkat cells expressing S1P1 and Gqi5, which allows for phospholipase C stimulation by Gi...
| Keywords: | S1P (d18:1), Sphingosine-1-Phosphoric Acid, 2S-amino-4E-octadecene-1,3R-diol 1-(dihydrogen phosphate) |
| Application: | Bioactive lipid assays |
| CAS | 26993-30-6 |
| MW: | 379.5 D |
From 100.00€
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Lipid-based Drug Delivery Tools
1-Palmitoyl-2-hydroxy-sn-glycero-3-PC
Item number: Cay10172-25
1-Palmitoyl-2-hydroxy-sn-glycero-3-PC is the ubiquitous lipid species generated following phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine. It increases the production of reactive oxygen species (ROS) and decreases superoxide dismutase (SOD) and endothelial nitric oxide synthase (eNOS) protein levels and...
| Keywords: | 16:0/0:0-PC, 1-Hexadecanoyl-sn-glycero-3-Phosphatidylcholine, 1-Hexadecanoyl-sn-glycero-3-Phosphocholine,... |
| Application: | Bioactive lipid assays |
| CAS | 17364-16-8 |
| MW: | 495.6 D |
From 61.00€
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Lipid-based Drug Delivery Tools
1,2-Distearoyl-sn-glycero-3-PC
Item number: Cay15100-1
1,2-Distearoyl-sn-glycero-3-PC (1,2-DSPC) is a phospholipid containing the saturated long-chain (18:0) stearic acid inserted at the sn-1 and sn-2 positions. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes. The transition temperature of 1,2-DSPC is approximately...
| Keywords: | 1,2-Distearoyl-sn-glycero-3-Phosphocholine, 1,2-DSPC, Coatsome MC 8080, 1,2-distearoyl-sn-glycero-3-phosphatidylcholine |
| Application: | Phospholipid |
| CAS | 816-94-4 |
| MW: | 790.2 D |
From 69.00€
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Lipid-based Drug Delivery Tools
1,2-Dimyristoyl-sn-glycero-3-PC
Item number: Cay15097-1
1,2-Dimyristoyl-sn-glycero-3-PC (DMPC) is a phospholipid containing 14:0 fatty acids at the sn-1 and sn-2 positions. It is a synthetic phosopholipid that has been used for liposome production in order to study the properties of lipid bilayer.Formal Name: 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine. CAS Number:...
| Keywords: | 1,2-Dimyristoyl-sn-glycero-3-Phosphocholine, 1,2-DMPC, 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine |
| Application: | Liposome production |
| CAS | 18194-24-6 |
| MW: | 677.9 D |
From 66.00€
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Lipid-based Drug Delivery Tools
C16 Sphingomyelin (d18:1/16:0)
Item number: Cay10007946-1
C16 Sphingomyelin is a naturally occurring sphingolipid. Levels of C16 sphingomyelin are elevated in the prefrontal cortex and cerebellum in a rat model of diabetes induced by streptozotocin (STZ, Cay-13104), as well as in the liver in mouse models of Niemann-Pick type C1 disease. Plasma levels of C16 sphingomyelin...
| Keywords: | N-Palmitoyl-D-erythro-Sphingosylphosphorylcholine, Palmitoyl Sphingomyelin, SM(d18:1/16:0), Sphingomyelin (d18:1/16:0),... |
| Application: | Bioactive Lipid Assays |
| CAS | 6254-89-3 |
| MW: | 703 D |
From 94.00€
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Lipid-based Drug Delivery Tools
1-Palmitoyl-2-Oleoyl-sn-glycero-3-PC
Item number: Cay15102-100
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (1,2-POPC) is a phospholipid containing 16:0 and 18:1 fatty acids at the sn-1 and sn-2 positions, respectively. It belongs to a class of phospholipids that are a major component of biological membranes. This compound can be used for liposome production in order to study the...
| Keywords: | 1,2-POPC, 1-Palmitoyl-2-Oleoyl-sn-glycero-3-Phosphocholine, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylcholine |
| Application: | Liposome production |
| CAS | 26853-31-6 |
| MW: | 760.1 D |
From 102.00€
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Lipid-based Drug Delivery Tools
1,2-Dioleoyl-sn-glycero-3-PE
Item number: Cay15091-100
1,2-Dioleoyl-sn-glycero-3-PE (1,2-DOPE) is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. The compound features the same diacylglycerol stereochemistry as that of the natural compound. 1,2-DOPE can be used as an emulsifier to facilitate DNA-liposome complex...
| Keywords: | 1,2-Dioleoyl-sn-glycero-3-Phosphoethanolamine, 1,2-DOPE, 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine |
| Application: | Emulsifier |
| CAS | 4004-05-1 |
| MW: | 744.1 D |
From 109.00€
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Lipid-based Drug Delivery Tools
ALC-0159
Item number: Cay34336-25
ALC-0159 is a lipid excipient. Formulations containing ALC-0159 have been used in the development of lipid nanoparticles (LNPs) for the delivery of mRNA-based vaccines.Formal Name: alpha-[2-(ditetradecylamino)-2-oxoethyl]-omega-methoxy-poly(oxy-1,2-ethanediyl). CAS Number: 1849616-42-7. Synonyms:...
| Keywords: | alpha-[2-(ditetradecylamino)-2-oxoethyl]-omega-methoxy-poly(oxy-1,2-ethanediyl) |
| Application: | Lipid excipient, mRNA-based vaccine delivery |
| CAS | 1849616-42-7 |
From 129.00€
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Lipid-based Drug Delivery Tools
LipidLaunch(TM) LNP-102 Exploration Kit
Item number: Cay35425-1
This kit, formerly known as Lipid Nanoparticle (LNP-102) Exploration Kit, has recently been renamed to join our line of research-ready LipidLaunch(TM) products for LNP applications. Cayman's LipidLaunch(TM) LNP-102 Exploration Kit is intended to serve as a starting point for laboratories to explore the feasibility...
| Application: | SM-102-containing LNP preparation |
354.00€
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Lipid-based Drug Delivery Tools
DLin-MC3-DMA
Item number: Cay34364-10
DLin-MC3-DMA is an ionizable cationic amino lipid (apparent pKa = 6.44) that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Administration of Factor VII siRNA in DLin-MC3-DMA-containing LNPs reduces plasma Factor VII protein levels in mice. Formulations containing...
| Keywords: | MC3, 4-(dimethylamino)-butanoic acid, (10Z,13Z)-1-(9Z,12Z)-9,12-octadecadien-1-yl-10,13-nonadecadien-1-yl ester |
| Application: | Ionizable amino lipid |
| CAS | 1224606-06-7 |
| MW: | 642.1 D |
From 32.00€
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Lipid-based Drug Delivery Tools
1-Stearoyl-2-hydroxy-sn-glycero-3-PC
Item number: Cay15107-100
1-Stearoyl-2-hydroxy-sn-glycero-3-PC is a saturated lysophosphatidylcholine. It increases IL-1beta production in isolated human blood monocytes when used at a concentration of 12.5 µM. Plasma levels of 1-stearoyl-2-hydroxy-sn-glycero-3-PC are decreased in patients with lung cancer.Formal Name:...
| Keywords: | 1-Octadecanoyl-2-hydroxy-sn-glycero-3-phosphatidylcholine, 1-Stearoyl-2-hydroxy-sn-glycero-3-Phosphocholine,... |
| Application: | Lysophosphatidylcholine |
| CAS | 19420-57-6 |
| MW: | 523.7 D |
From 84.00€
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Lipid-based Drug Delivery Tools
D-erythro Lysosphingomyelin (d18:1)
Item number: Cay10007947-1
D-erythro Lysosphingomyelin is a bioactive sphingolipid. It is an agonist of sphingosine-1-phosphate receptor 1 (S1P1), S1P2, and S1P3 (EC50s = 167.7, 368.1, and 482.6 nM, respectively, for the human receptors). D-erythro Lysosphingomyelin is also an agonist of the orphan receptor ovarian cancer G protein-coupled...
| Keywords: | D-erythro Lyso SM(18:1), D-erythro Sphingosine-1-Phosphocholine (d18:1), D-erythro-Sphingophosphorylcholine,... |
| Application: | Bioactive Lipid Assays |
| CAS | 1670-26-4 |
| MW: | 464.6 D |
From 121.00€
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