47 products were found matching "968"!

This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane...

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. This mAb recognizes protein of 26kDa-60kDa, which is identified as CD63. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific...

Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. This mAb recognizes protein of 26kDa-60kDa, which is identified as CD63. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of...

1 mg/ml in sterile PBS, BSA free, sodium azide free. This mAb recognizes protein of 26kDa-60kDa, which is identified as CD63. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific...

Description: Glutaminase C-IN-1 (Compound 968) is an allosteric inhibitor of Glutaminase C (GLS1). Target: Glutaminase. Smiles: CN(C)c1ccc(cc1Br)C1Nc2ccc3ccccc3c2C2=C1C(=O)CC(C)(C)C2. References: Stalnecker CA, et al. Mechanism by which a recently discovered allosteric inhibitor blocks glutamine metabolism in...

PathPlex Panel 4 identifies total T-cells (CD3), cytotoxic T-cells (CD8) and regulatory T-cells (FoxP3) within the context of the tumor microenvironment. Antigen presenting cells such as macrophages (CD68) or tumor cells (cytokeratin) express immune checkpoint ligands such as PD-L1 which inhibits the ability of...

PathPlex Panel 5 identifies total T-cells (CD3), cytotoxic T-cells (CD8) and cells expressing the immune checkpoint ligand PD-L1 within the context of the tumor microenvironment. PD-L1 can be expressed on antigen presenting cells such as macrophages (CD68) or tumor cells (cytokeratin). Ki-67 is a proliferation...

Protein function: Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules, this occurs in a transporter associated with antigen processing (TAP)-independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus...

Protein function: Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'- 5' exonuclease and 3'-phosphodiesterase, but not apurinic-...

Description: H3B-968 is a potent inhibitor of Werner syndrome protein (WRN) with an IC50 of approximately 10 nM, targeting its helicase, ATPase, and exonuclease activities. While WRN is known for its synthetic lethal activity in cancer studies, H3B-968 specifically inhibits WRN's helicase function through...