InVivoKines™ are a new generation of fusion proteins with improved activity and stability for your in vivo research! They enable scientists to delve deeper into the complex world of cytokines in living organisms, gaining new insights and opening doors to effective therapies. Learn more about the technology behind InVivoKines™ and get an overview of the different product types and their applications.
Inflammasomes are multi-protein complexes whose activity has been implicated in physiological and pathological inflammation. The hallmarks of inflammasome activation are the maturation of the cytokines IL-1β and IL-18, and the processing of gasdermin D to mediate cytokine release and pyroptosis from cells of the innate immune system.
Progranulin is a stress-induced protein with multifunctional biological activities, including major roles in cancer, inflammation, metabolic diseases and neurodegeneration.
Pyroptosis is an inflammatory programmed cell death, which is induced by inflammatory caspases. During this process, Gasdermin D (GSDMD) is a central mediator of pyroptotic cell death.