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![Ubiquitin (human, recombinant)](https://www.biomol.com/media/image/94/fd/3f/Cay20487-1_600x600.png)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay20487-1 | 1 mg | - |
6 - 10 business days* |
161.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Ubiquitin is a regulatory protein encoded by three gene classes in humans, which code for fusion... more
Product information "Ubiquitin (human, recombinant)"
Ubiquitin is a regulatory protein encoded by three gene classes in humans, which code for fusion proteins between ubiquitin and zinc-finger proteins, ribosomal proteins, or ubiquitin repeats that are cleaved by esterases to release monomeric ubiquitin. It is ubiquitously expressed and highly conserved among eukaryotic species. Ubiquitin is conjugated to misfolded, abnormal, short-lived, or foreign proteins by ubiquitin-conjugating enzymes (E2) and substrate-specific ubiquitin ligases (E3) to target them for degradation by the 26S proteasome or lysosome. It is also conjugated to proteins to modify cell signaling through regulation of protein-protein interactions, activity, or subcellular localization. Dysregulation of ubiquitination has been implicated in the pathogenesis of neurodegenerative diseases, including Parkinson's and Alzheimer's diseases. Cayman's Ubiquitin (human, recombinant) protein can be used as a substrate for enzyme activity assays.Purity: >95% estimated by SDS-PAGE. Source: Recombinant human ubiquitin expressed in E. coli. Amino Acids: 1-76. MW: 8.5 kDa. Formulation: (Request formulation change), 50 mM Tris, pH 7.5, with 150 mM sodium chloride and 5% glycerol. UniProt Accession #: P0CG48.
Keywords: | UBC, Ubiquitin, Polyubiquitin-C |
Supplier: | Cayman Chemical |
Supplier-Nr: | 20487 |
Properties
Application: | Enzyme activity |
Conjugate: | No |
Host: | E.coli |
MW: | 8.6 kD |
Purity: | >95% estimated by SDS-PAGE |
Format: | Solution |
Database Information
KEGG ID : | K08770 | Matching products |
UniProt ID : | P0CG48 | Matching products |
Gene ID | GeneID 7316 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -80°C (International: -80°C) |
Signal Word: | Warning |
H Phrases: | H316 |
P Phrases: | P332+P313 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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