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![Sulfotransferase 1A3, Cytosolic, Recombinant, Human (SULT1A3)](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
S8022-03B.20 | 20 µg | - | - |
3 - 19 business days* |
909.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Cytosolic sulfotransferases are a family of Phase II drugmetabolizing enzymes that catalyze the... more
Product information "Sulfotransferase 1A3, Cytosolic, Recombinant, Human (SULT1A3)"
Cytosolic sulfotransferases are a family of Phase II drugmetabolizing enzymes that catalyze the sulfation of many endogenous and xenobiotic substrates (13). They have important roles in the metabolism of many endogenous compounds including steroids, bile acids, thyroid hormones and monoamine neurotransmitters. They are widely distributed throughout the body and serve to inactivate and increase watersolubility of xenobiotics and therapeutic drugs. They are distinct from Golgi resident sulfotransferases by lacking N terminal signalanchor domains and residing only in the cytoplasm. SULT1A3 catalyzes the sulfation of phenolic monoamines, such as dopamine, norepinephrine and serotonin, and phenolic and catecholic drugs (4, 5). SULT1A3 is also called catecholamine sulfotransferase. Recombinant enzyme corresponding to aa2-295 with an N-terminal Met and 6-His tag expressed in E. coli (P50224). , N-terminal Sequence Analysis: , Met , SDS-PAGE: 34kD, reducing conditions, Activity: Measured by its ability to transfer sulfate from PAPS to 1-Napthol. Specific Activity: >15pmoles/min/ug, as measured under the described conditions (see Protocol). Stability & Storage: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | STM, M-PST, HAST3, TL-PST, SULT1A3, EC=2.8.2.1, ST1A3/ST1A4, Sulfotransferase 1A3/1A4, Aryl sulfotransferase 1A3/1A4, Placental estrogen sulfotransferase, Thermolabile phenol sulfotransferase, Sulfotransferase, monoamine-preferring |
Supplier: | United States Biological |
Supplier-Nr: | S8022-03B |
Properties
Conjugate: | No |
Species reactivity: | human |
Database Information
KEGG ID : | K01014 | Matching products |
UniProt ID : | P50224 | Matching products |
Gene ID | GeneID 101929857 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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