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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay10011669-50 | 50 µg | - |
6 - 10 business days* |
526.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Soluble epoxide hydrolase (sEH) is a member of the alpha/beta-hydrolase fold enzyme family that... more
Product information "Soluble Epoxide Hydrolase (human, recombinant)"
Soluble epoxide hydrolase (sEH) is a member of the alpha/beta-hydrolase fold enzyme family that catalyzes the hydrolysis of bioactive fatty acid epoxides to inactive vicinal diols. It is a homodimer in which each subunit is composed of two domains, a C-terminal epoxide hydrolase domain and an N-terminal phosphatase domain. sEH is localized to the cytoplasm or to peroxisomes in a tissue-specific manner and is found in various tissues, including skin, lung, uterus, kidney, brain, and myocardium. sEH is also expressed in the vasculature and inhibition of sEH attenuates pathogenic vascular remodeling and hypertension via preservation of cardioprotective epoxyeicosatrienoic acids (EETs) in rat models of atherosclerosis and hypertension, respectively. Inhibition of sEH also has a protective role in various diseases, including inflammatory bowel disease, osteoarthritis, seizure, stroke, and Alzheimer's disease, as well as in various chronic pain states. Cayman's Soluble Epoxide Hydrolase (human, recombinant) protein can be used for enzyme activity assays.Synonyms: Cytosolic Epoxide Hydrolase (CEH), EPHX2, Epoxide Hydrolase 2, sEH. Purity: >95% estimated by SDS-PAGE. Source: Active recombinant human N-terminal His-tagged sEH expressed in insect cells. Amino Acids: 2-555 (full length). MW: 64 kDa. Formulation: (Request formulation change), TBS, pH 7.4, with 20% glycerol. Host: Insect cells. UniProt Accession #: P34913.
Keywords: | CEH, CEH, Epoxide hydratase, Epoxide hydratase, Lipid-phosphate phosphatase, Lipid-phosphate phosphatase, Cytosolic epoxide hydrolase 2, Cytosolic epoxide hydrolase 2, Bifunctional epoxide hydrolase 2 {ECO:0000305}, Bifunctional epoxide hydrolase 2 {ECO:0 |
Supplier: | Cayman Chemical |
Supplier-Nr: | 10011669 |
Properties
Application: | Enzyme activity |
Conjugate: | No |
MW: | 64 kD |
Purity: | >95% estimated by SDS-PAGE |
Database Information
KEGG ID : | K08726 | Matching products |
UniProt ID : | P34913 | Matching products |
Gene ID : | GeneID 2053 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -80°C (International: -80°C) |
Signal Word: | Warning |
H Phrases: | H316 |
P Phrases: | P332+P313 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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