Small conductance calcium-activated potassium channel protein 2 (Kcnn2), partial, mouse, recombinant

Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-376aa. Protein Length: Partial. Tag Info: C-terminal 6xHis-GFP-tagged. Target Protein Sequence: MPIVLVRPTN RTRRLDSTGA GMGPSSHQQQ ESPLPTITHC AGCTTAWSPC SFNSSDMETP LQFQRGFFPE QPPPPPRSSH LHCQQQQQSQ DKPCAPFAPL PHPHHHPHLA HQQPGSGGSS PCLRCNSCAS SGAPAAGAGA GDNLSLLLRT SSPGGAFRTR TSSPLSGSSC CCCCSSRRGS QLNVSELTPS SHASALRQQY AQQPASASQY HQCHSLQPAT SPTGSLGSLG SGPPLSHHHH HPHPAHHQHH QPQARRESNP FTEIAMSSCR YNGGVMRPLS NLSSSRRNLQ EMDSEAQPLQ PPASVVGGGG GASSPSAAAA ASSSAPEIVV SKPEHNNSNN LALYGTGGGG STGGGGGGSG HGSSSGTKSS KKKNQN. Purity: Greater than 85% as determined by SDS-PAGE. Endotoxin: n/a. Biological Activity: n/a. Form: Liquid or Lyophilized powder. Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50%. Customers could use it as reference. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 °C/-80 °C. The shelf life of lyophilized form is 12 months at -20 °C/-80 °C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week. Relevance: Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. Reference: n/a. Function: nan