SMAD2 Protein, Human, Recombinant (His & SUMO)

Item number	Size	Manual	Delivery time	Price
TGM-TMPH-01699-20ug	20 µg	-	7 - 10 business days*	198.00€
TGM-TMPH-01699-100ug	100 µg	-	7 - 10 business days*	387.00€
TGM-TMPH-01699-1mg	1 mg		7 - 10 business days*	1,681.00€

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Description: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and... more

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Product information "SMAD2 Protein, Human, Recombinant (His & SUMO)"

Description: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

Keywords:	JV18-1, SMAD2, SMAD family member 2, Mad-related protein 2, Mothers against decapentaplegic homolog 2
Supplier:	TargetMol
Supplier-Nr:	TMPH-01699

Properties

Conjugate:	No
MW:	68.2 kD

Database Information

KEGG ID :	K04500 \| Matching products
UniProt ID :	Q15796 \| Matching products
Gene ID :	GeneID 4087 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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