SGPL1 PrEST Antigen

SGPL1 PrEST Antigen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-APrEST74229.100 100 µl - -

7 - 10 business days*

247.00€
 
Protein function: Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate,... more
Product information "SGPL1 PrEST Antigen"
Protein function: Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis (PubMed:11018465, PubMed:14570870, PubMed:24809814, PubMed:28165339). Required for global lipid homeostasis in liver and cholesterol homeostasis in fibroblasts. Involved in the regulation of pro- inflammatory response and neutrophil trafficking. Modulates neuronal autophagy via phosphoethanolamine production which regulates accumulation of aggregate-prone proteins such as APP. Seems to play a role in establishing neuronal contact sites and axonal maintenance. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: hSPL, S1PL, SPL 1, SP-lyase 1, Sphingosine-1-phosphate lyase 1, Sphingosine-1-phosphate aldolase
Supplier: Atlas Antibodies
Supplier-Nr: APrEST74229

Properties

Application: Control antigen
Conjugate: No
Host: E.coli
Species reactivity: human

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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