SARS-CoV-2 Nucleocapsid Protein, His-SUMOtag, HEK293

Sequence: MSDNGPQNQR NAPRITFGGP SDSTGSNQNG ERSGARSKQR RPQGLPNNTA SWFTALTQHG KEDLKFPRGQ GVPINTNSSP ATRRIRGGDG KMKDLSPRWY FYYLGTGPEA GLPYGANKGI IWVATEGALN TPKDHIGTRN PANNAAIVLQ LPQGTTLPKG FYAEGSRGGS ASSRSSSRSR NSSRNSTPGS SRGTSPARMA GNGGDAALAL LLLDRLNQLE SKMSGKGQQQ QGQTVTKKSA AEASKPRQKR QAFGRRGPEQ TQGNFGDQEL IRQGTDYKHW PQIAQFAPSA SAFFGMSRIG MEVTPSGTWL TYTGAIKLDD KDPNFKDQVI LLNKHIDAYK FPPTEPKKDK KKKADETQAL PRQKKQQTVT LLPAADLDDF SKQLQQSMSS with polyhistidine-SUMO tag at the N-terminus. Endotoxin level: <0.1 EU per 1 µg of the protein by the LAL method. Protein function: Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. May modulate transforming growth factor-beta signaling by binding host smad3. [The UniProt Consortium]