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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-32-8654-10 | 10 µg | - | - |
3 - 11 business days* |
546.00€
|
||
ABE-32-8654-50 | 50 µg | - | - |
3 - 11 business days* |
979.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Source: Human Cells. MW :26.1kD. Recombinant Mouse Kallikrein 7 is produced by our Mammalian... more
Product information "Recombinant Mouse Kallikrein 7/KLK7 (C-6His)"
Source: Human Cells. MW :26.1kD. Recombinant Mouse Kallikrein 7 is produced by our Mammalian expression system and the target gene encoding Gln22-Arg249 is expressed with a 6His tag at the C-terminus. Kallikrein7, also named as stratum corneum chymotryptic enzyme (SCCE), is a secreted protein of the Kallikrein-related peptidase (KLK) family. This family contains fifteen homologous secreted serine endopeptidases and plays a significant role in various physiological processes, including skin desquamation, semen liquefaction, neural plasticity, and body fluid homeostasis. In skin KLK5, KLK 7 and KLK14 are able to degrade corneodesmosomes, which leads to desquamation of skin surface cells. KLK activation is believed to be mediated through highly organized proteolytic cascades, regulated through a series of feedback loops, inhibitors, auto-degradation and internal cleavages. Studies have shown that one potential physiological activator for KLK7 is KLK5. Along with KLK14, these three kallikreins form a proteolytic cascade in the stratum corneum. KLK7 is primarily expressed in the skin but is also detected at relatively high levels in esophagus, heart, liver, central nervous system, kidney, pancreas, mammary and salivary glands. Protein function: May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-, -Gln-15' and insulin B chain at '6- Leu-, -Cys-7', '16-Tyr-, -Leu-17', '25-Phe-, -Tyr-26' and '26-Tyr-, - Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines. [The UniProt Consortium]
Supplier: | Abeomics |
Supplier-Nr: | 32-8654 |
Properties
Conjugate: | No |
Database Information
KEGG ID : | K08668 | Matching products |
UniProt ID : | Q91VE3 | Matching products |
Gene ID : | GeneID 23993 | Matching products |
Handling & Safety
Storage: | +20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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