Recombinant Human OX40/TNFRSF4/CD134 (C-6His)

Recombinant Human OX40/TNFRSF4/CD134 (C-6His)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-32-8628-10 10 µg - -

3 - 11 business days*

463.00€
ABE-32-8628-50 50 µg - -

3 - 11 business days*

747.00€
 
Source: Human Cells. MW :21kD. Recombinant Human OX40 is produced by our Mammalian expression... more
Product information "Recombinant Human OX40/TNFRSF4/CD134 (C-6His)"
Source: Human Cells. MW :21kD. Recombinant Human OX40 is produced by our Mammalian expression system and the target gene encoding Leu29-Ala216 is expressed with a 6His tag at the C-terminus. OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases. Protein function: Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity. [The UniProt Consortium]
Supplier: Abeomics
Supplier-Nr: 32-8628

Properties

Conjugate: No

Handling & Safety

Storage: +20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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