Recombinant Human Isocitrate Dehydrogenase 1/IDH1 (R132H, C-8His)

Recombinant Human Isocitrate Dehydrogenase 1/IDH1 (R132H, C-8His)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-32-8701-10 10 µg - -

3 - 11 business days*

546.00€
ABE-32-8701-50 50 µg - -

3 - 11 business days*

979.00€
 
Source: E.coli. MW :48.1kD. Recombinant Human Isocitrate Dehydrogenase is produced by our E.coli... more
Product information "Recombinant Human Isocitrate Dehydrogenase 1/IDH1 (R132H, C-8His)"
Source: E.coli. MW :48.1kD. Recombinant Human Isocitrate Dehydrogenase is produced by our E.coli expression system and the target gene encoding Met1-Leu414 is expressed with a 8His tag at the C-terminus. Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 exists as a homodimer, binding one magnesium or manganese ion per subunit. Mutations of IDH1 have been shown to cause metaphyseal chondromatosis with aciduria and are involved in the development of glioma. IDH plays a role in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the a-hydroxylation of phytanic acid.
Supplier: Abeomics
Supplier-Nr: 32-8701

Properties

Conjugate: No

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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