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![Recombinant Human c-Yes/YES1 Protein (His & GST Tag)(Active) (RPES1085)](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
G-RPES1085.50 | 50 µg | - | - | - |
9 - 20 business days* |
994.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Human c-Yes/YES1 Recombinant Protein (RPES1085) is a highly pure recombinant protein developed by... more
Product information "Recombinant Human c-Yes/YES1 Protein (His & GST Tag)(Active) (RPES1085)"
Human c-Yes/YES1 Recombinant Protein (RPES1085) is a highly pure recombinant protein developed by Assay Genie for use in a range of applications Protein function: Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. Stimulation by receptor tyrosine kinases (RTKs) including EGRF, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates. Upon EGFR activation, promotes the phosphorylation of PARD3 to favor epithelial tight junction assembly. Participates in the phosphorylation of specific junctional components such as CTNND1 by stimulating the FYN and FER tyrosine kinases at cell-cell contacts. Upon T-cell stimulation by CXCL12, phosphorylates collapsin response mediator protein 2/DPYSL2 and induces T-cell migration. Participates in CD95L/FASLG signaling pathway and mediates AKT-mediated cell migration. Plays a role in cell cycle progression by phosphorylating the cyclin-dependent kinase 4/CDK4 thus regulating the G1 phase. Also involved in G2/M progression and cytokinesis. [The UniProt Consortium]
Keywords: | YES, YES1, p61-Yes, EC=2.7.10.2, Proto-oncogene c-Yes, Tyrosine-protein kinase Yes |
Supplier: | Assay Genie |
Supplier-Nr: | RPES1085 |
Properties
Conjugate: | No |
Host: | Insect cells |
Species reactivity: | human |
Format: | Highly Purified |
Database Information
KEGG ID : | K05705 | Matching products |
UniProt ID : | P07947 | Matching products |
Gene ID | GeneID 7525 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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