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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-PKSV030104.100 | 100 µg | - |
7 - 16 business days* |
1,313.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein Construction: A DNA sequence encoding the SARS-CoV (strain WH20) papain-like protease... more
Product information "Plpro/papain-like protease (His Tag) (recombinant sars-cov)"
Protein Construction: A DNA sequence encoding the SARS-CoV (strain WH20) papain-like protease (PLpro) (AAX16193.1) (Glu1541-Tyr1859) was expressed with a polyhistidine tag at the C-terminus. Sequence: Glu1541-Tyr1859. Fusion tag: C-His Endotoxin: Please contact us for more information. Protein function: The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. Targeting PLpro with antiviral drugs may have an advantage in not only inhibiting viral replication but also inhibiting the dysregulation of signaling cascades in infected cells that may lead to cell death in surrounding, uninfected cells. Protein function: [Isoform Replicase polyprotein 1ab]: Multifunctional protein involved in the transcription and replication of viral RNAs. Contains the proteinases responsible for the cleavages of the polyprotein. [The UniProt Consortium]
Keywords: | rep, 1a-1b, EC=3.1.-.-, EC=2.1.1.-, EC=3.6.4.13, EC=3.4.22.-, EC=2.7.7.48, EC=3.1.13.-, EC=3.6.4.12, EC=3.4.22.69, EC=3.4.19.12, Recombinant SARS-CoV Plpro/papain-like protease (His Tag) |
Supplier: | Elabscience |
Supplier-Nr: | E-PKSV030104 |
Properties
Conjugate: | No |
Host: | E.coli |
Species reactivity: | sars-cov |
MW: | 36.65 kD |
Format: | Lyophilized |
Database Information
KEGG ID : | K24149 | Matching products |
UniProt ID : | P0C6X7 | Matching products |
Gene ID | GeneID 1489680 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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