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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-32-18517-50 | 50 µg | - | - |
3 - 11 business days* |
1,028.00€
|
||
ABE-32-18517-100 | 100 µg | - | - |
3 - 11 business days* |
1,317.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Recombinant Canine PD-L1 protein with C-terminal human Fc tag Background: This gene... more
Product information "PD-L1 Protein (canine), hFc Tag"
Description: Recombinant Canine PD-L1 protein with C-terminal human Fc tag Background: This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. Molecular Characterization: mass of 51.1 kDa after removal of the signal peptide. Tag: C-Human Fc tag
Keywords: | Programmed death ligand 1, Canine PD-L1 Protein, hFc Tag |
Supplier: | Abeomics |
Supplier-Nr: | 32-18517 |
Properties
Conjugate: | No |
Host: | Human cells |
Species reactivity: | dog |
Purity: | >95% (SDS-PAGE) |
Format: | Lyophilized |
Database Information
KEGG ID : | K06745 | Matching products |
UniProt ID : | E2RKZ5 | Matching products |
Gene ID : | GeneID 484186 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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