OX40:Fc, Recombinant, Human (TNFRSF 4, Tumor Necrosis Factor Receptor Superfamily Member 4, CD134)

OX40:Fc, Recombinant, Human (TNFRSF 4, Tumor Necrosis Factor Receptor Superfamily Member 4, CD134)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
045123.50 50 µg - -

3 - 19 business days*

531.00€
 
OX40 binds to receptors on T-cells, preventing them from dying and subsequently increasing... more
Product information "OX40:Fc, Recombinant, Human (TNFRSF 4, Tumor Necrosis Factor Receptor Superfamily Member 4, CD134)"
OX40 binds to receptors on T-cells, preventing them from dying and subsequently increasing cytokine production. OX40 has a critical role in the maintenance of an immune response. OX40:Fc was shown to prevent OX40 from reaching the T-cell receptors, thus reducing the T-cell response. Experiments in mice have demonstrated that OX40:Fc can reduce the symptoms associated with the cytokine storm (an immune overreaction) while allowing the immune system to fight off the virus successfully. Biological Activity: Blocks T cell proliferation induced by CD134L. Sequence: Human OX40 (aa 29-214) is fused at the C-terminus to the Fc portion of human IgG1. Storage and Stability: Short-term Storage: +4°C, Long-term Storage: -20°C, Stable for at least 6 months after receipt when stored at -20°C.
Keywords: CD134, TXGP1L, TNFRSF4, ACT35 antigen, OX40L receptor, Tumor necrosis factor receptor superfamily member 4, TAX transcriptionally-activated glycoprotein 1 receptor
Supplier: United States Biological
Supplier-Nr: 045123

Properties

Conjugate: No
Species reactivity: human
Format: Highly Purified

Handling & Safety

Storage: vT
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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