Merlin Protein, Human, Recombinant (His)

Item number	Size	Manual	Delivery time	Price
TGM-TMPH-01662-20ug	20 µg	-	7 - 10 business days*	278.00€
TGM-TMPH-01662-100ug	100 µg	-	7 - 10 business days*	526.00€
TGM-TMPH-01662-1mg	1 mg	-	7 - 10 business days*	2,257.00€

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Description: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling... more

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Product information "Merlin Protein, Human, Recombinant (His)"

Description: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex.

Keywords:	Moesin-ezrin-radixin-like protein, Merlin, Schwannomin, Schwannomerlin, Neurofibromin-2, NF2
Supplier:	TargetMol
Supplier-Nr:	TMPH-01662

Properties

Conjugate:	No
MW:	73.7 kD

Database Information

KEGG ID :	K16684 \| Matching products
UniProt ID :	P35240 \| Matching products
Gene ID :	GeneID 4771 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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