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![Lck, p56lck, active, Recombinant, Human (Lymphocyte-specific Tyrosine Kinase)](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
L1565-06C.10 | 10 µg | - | - |
3 - 19 business days* |
1,037.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
LCK (p56lck) is a member of the Src family of non-receptor tyrosine kinases. It was identified as... more
Product information "Lck, p56lck, active, Recombinant, Human (Lymphocyte-specific Tyrosine Kinase)"
LCK (p56lck) is a member of the Src family of non-receptor tyrosine kinases. It was identified as a gene rearranged and over-expressed in the murine lymphoma LSTRA, most likely as a result of the insertion of Moloney murine leukemia virus DNA immediately adjacent to the gene (1). LCK behaves as a proto-oncogene and can lead to cell transformation upon activation. A number of human cancer cell lines show over-expression of LCK, pointing to a possible role for this kinase in the initiation and maintenance of the transformed state in human cancers (2). Source: Recombinant full-length human LCK was expressed by baculovirus in Sf 9 insect cells using an N-terminal GST tag. The gene accession number is NM_005356. , Molecular Mass: The approximate molecular weight is 84 kD. Activity: The specific activity of LCK was determined to be 239 nmol/min/mg using a Poly (Glu:Tyr, 4:1) synthetic peptide substrate (see activity assay protocol). , Storage: This product is stable at < -70° C for at least 6 months from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.
Keywords: | LSK, LCK, p56-LCK, EC=2.7.10.2, Protein YT16, Proto-oncogene Lck, Tyrosine-protein kinase Lck, Leukocyte C-terminal Src kinase, T cell-specific protein-tyrosine kinase, Lymphocyte cell-specific protein-tyrosine kinase |
Supplier: | United States Biological |
Supplier-Nr: | L1565-06C |
Properties
Conjugate: | No |
Species reactivity: | human |
Format: | Highly Purified |
Database Information
KEGG ID : | K05856 | Matching products |
UniProt ID : | P06239 | Matching products |
Gene ID | GeneID 3932 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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