Human TNFRSF10B Protein, mFc Tag

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Item number	Size	Manual	SDS	Delivery time	Price
DIM-PME100465.10	10 µg	-	-	7 - 16 business days*	109.00€
DIM-PME100465.50	50 µg	-	-	7 - 16 business days*	434.00€
DIM-PME100465.100	100 µg	-	-	7 - 16 business days*	644.00€

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Recombinant human TNFRSF10B protein with C-terminal mouse Fc tag. TNFRSF10B (Ile56-Glu182)... more

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Product information "Human TNFRSF10B Protein, mFc Tag"

Recombinant human TNFRSF10B protein with C-terminal mouse Fc tag. TNFRSF10B (Ile56-Glu182) mFc(Pro99-Lys330), Protein function: Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:10549288). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis. [The UniProt Consortium]

Keywords:	TNFRSF10B, TRAILR2, TRAIL-R2, CD262, DR5, KILLER, TRICK2, ZTNFR9, TRICKB
Supplier:	DIMA
Supplier-Nr:	PME100465

Properties

Conjugate:	No
Host:	Human cells
Species reactivity:	human
MW:	40.5 kD
Purity:	>95% (SDS-PAGE)
Format:	Lyophilized

Database Information

KEGG ID :	K04722 \| Matching products
UniProt ID :	O14763 \| Matching products
Gene ID	GeneID 8795 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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