Human MDR-1 Protein, hFc Tag

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Item number	Size	Manual	SDS	Delivery time	Price
DIM-PME100589.10	10 µg	-	-	7 - 16 business days*	101.00€
DIM-PME100589.50	50 µg	-	-	7 - 16 business days*	384.00€
DIM-PME100589.100	100 µg	-	-	7 - 16 business days*	575.00€

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Recombinant Human MDR-1 with C-terminal human Fc tag. MDR-1(Phe72-Arg113) (Lys213-Thr215)... more

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Product information "Human MDR-1 Protein, hFc Tag"

Recombinant Human MDR-1 with C-terminal human Fc tag. MDR-1(Phe72-Arg113) (Lys213-Thr215) (Thr318-Gln330) (Gly960-Asp973) hFc(Glu99-Ala330), Protein function: Translocates drugs and phospholipids across the membrane (PubMed:8898203, PubMed:2897240, PubMed:9038218). Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins (PubMed:8898203). Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells (PubMed:2897240, PubMed:9038218). [The UniProt Consortium]

Keywords:	ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1
Supplier:	DIMA
Supplier-Nr:	PME100589

Properties

Conjugate:	No
Host:	Human cells
Species reactivity:	human
MW:	34.2 kD
Purity:	>95% (SDS-PAGE)
Format:	Lyophilized

Database Information

CAS :	12\| Matching products
KEGG ID :	K05658 \| Matching products
UniProt ID :	P08183 \| Matching products
Gene ID	GeneID 5243 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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