Human MDR-1 (72-113) Protein, hFc Tag

Human MDR-1 (72-113) Protein, hFc Tag
Item number Size Datasheet Manual SDS Delivery time Quantity Price
DIM-PME100601.10 10 µg - -

7 - 16 business days*

95.00€
DIM-PME100601.50 50 µg - -

7 - 16 business days*

363.00€
DIM-PME100601.100 100 µg - -

7 - 16 business days*

545.00€
 
Recombinant Human MDR-1(Phe72-Arg113) with C-terminal human Fc tag. MDR-1(Phe72-Arg113)... more
Product information "Human MDR-1 (72-113) Protein, hFc Tag"
Recombinant Human MDR-1(Phe72-Arg113) with C-terminal human Fc tag. MDR-1(Phe72-Arg113) hFc(Glu99-Ala330), Protein function: Translocates drugs and phospholipids across the membrane (PubMed:8898203, PubMed:2897240, PubMed:9038218). Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins (PubMed:8898203). Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells (PubMed:2897240, PubMed:9038218). [The UniProt Consortium]
Keywords: ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1
Supplier: DIMA
Supplier-Nr: PME100601

Properties

Conjugate: No
Host: Human cells
Species reactivity: human
MW: 30.9 kD
Purity: >95% (SDS-PAGE)
Format: Lyophilized

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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