Human KRAS Protein, hFc Tag

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Item number	Size	Manual	SDS	Delivery time	Price
DIM-PME100970.10	10 µg	-	-	7 - 16 business days*	109.00€
DIM-PME100970.50	50 µg	-	-	7 - 16 business days*	434.00€
DIM-PME100970.100	100 µg	-	-	7 - 16 business days*	644.00€

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Recombinant Human KRAS with C-terminal human Fc tag. KRAS(Thr2-Cys185) hFc(Glu99-Ala330), Protein... more

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Product information "Human KRAS Protein, hFc Tag"

Recombinant Human KRAS with C-terminal human Fc tag. KRAS(Thr2-Cys185) hFc(Glu99-Ala330), Protein function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:20949621). Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306). [The UniProt Consortium]

Keywords:	C-K-RAS, c-Ki-ras2, CFC2, K-Ras, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RALD, RASK2
Supplier:	DIMA
Supplier-Nr:	PME100970

Properties

Conjugate:	No
Host:	Human cells
Species reactivity:	human
MW:	47.1 kD
Purity:	>95% (SDS-PAGE)
Format:	Lyophilized

Database Information

CAS :	12\| Matching products
KEGG ID :	K07827 \| Matching products
UniProt ID :	P01116 \| Matching products
Gene ID	GeneID 3845 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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