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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-RPES6065.20 | 20 µg | - | - | - |
9 - 20 business days* |
320.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B,... more
Product information "Human ILT4/LILRB2 Recombinant Protein (His tag)"
Protein function: Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles (PubMed:11169396, PubMed:12853576, PubMed:16455647, PubMed:20448110, PubMed:27859042). Involved in the down-regulation of the immune response and the development of tolerance. Recognizes HLA-G in complex with B2M/beta-2 microglobulin and a nonamer self-peptide (peptide-bound HLA-G-B2M) triggering differentiation of type 1 regulatory T cells and myeloid-derived suppressor cells, both of which actively maintain maternal-fetal tolerance (PubMed:16455647, PubMed:20448110, PubMed:27859042). Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions (PubMed:11875462, PubMed:12853576, PubMed:9548455, PubMed:9842885). [The UniProt Consortium]
| Keywords: | CD85d, LIR-2, ILT-4, MIR-10, Immunoglobulin-like transcript 4, CD85 antigen-like family member D, Leukocyte immunoglobulin-like receptor 2, Monocyte/macrophage immunoglobulin-like receptor 10, Leukocyte immunoglobulin-like receptor subfamily B member 2 |
| Supplier: | Assay Genie |
| Supplier-Nr: | RPES6065 |
Properties
| Conjugate: | No |
| Host: | Human cells |
| Species reactivity: | human |
| Format: | Lyophilized |
Database Information
| KEGG ID : | K06512 | Matching products |
| UniProt ID : | Q8N423 | Matching products |
| Gene ID | GeneID 10288 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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