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![Human cyclin D3/CCND3 Recombinant Protein (His tag)](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
G-RPES5527.20 | 20 µg | - | - | - |
9 - 20 business days* |
159.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and... more
Product information "Human cyclin D3/CCND3 Recombinant Protein (His tag)"
Protein function: Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition (PubMed:8114739). Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase (PubMed:8114739). Hypophosphorylates RB1 in early G(1) phase (PubMed:8114739). Cyclin D- CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals (PubMed:8114739). Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex (PubMed:16782892). Shows transcriptional coactivator activity with ATF5 independently of CDK4 (PubMed:15358120). [The UniProt Consortium]
Keywords: | G1/S-specific cyclin-D3 |
Supplier: | Assay Genie |
Supplier-Nr: | RPES5527 |
Properties
Conjugate: | No |
Host: | E.coli |
Species reactivity: | human |
Format: | Lyophilized |
Database Information
KEGG ID : | K10152 | Matching products |
UniProt ID : | P30281 | Matching products |
Gene ID | GeneID 896 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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