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Product information "Human CD8 alpha&beta Heterodimer Protein"
Recombinant Human CD8 alpha&beta Heterodimer Protein is expressed from HEK293 with His tag and Flag tag at the C-Terminus.It contains Ser22-Asp182(CD8 alpha) acidic tail and Leu22-Pro170(CD8 beta) basic tail. CD8 alpha&beta (CD8alphabeta) is a heterodimeric form of CD8. CD8alpha is required for surface expression of CD8beta. The extracellular IgV-like domain of CD8alpha interacts with the alpha3 portion of the class I MHC molecule. CD8alphabeta is expressed on human peripheral T cells and functions as a coreceptor and can greatly increase the sensitivity and breadth of antigen recognition by CD8+ peripheral T cells bearing TCR.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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