Human CD46 Protein, His Tag

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Item number	Size	Manual	SDS	Delivery time	Price
DIM-PME100102.10	10 µg	-	-	7 - 16 business days*	101.00€
DIM-PME100102.50	50 µg	-	-	7 - 16 business days*	384.00€
DIM-PME100102.100	100 µg	-	-	7 - 16 business days*	575.00€

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Recombinant human CD46 Protein with C-terminal 6×His tag. CD46(Cys35-Tyr328) 6×His tag, Protein... more

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Product information "Human CD46 Protein, His Tag"

Recombinant human CD46 Protein with C-terminal 6×His tag. CD46(Cys35-Tyr328) 6×His tag, Protein function: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. [The UniProt Consortium]

Keywords:	CD46, AHUS2, MCP, MIC10, TLX, TRA2.10
Supplier:	DIMA
Supplier-Nr:	PME100102

Properties

Conjugate:	No
Host:	Human cells
Species reactivity:	human
MW:	33.5 kD
Purity:	>95% (SDS-PAGE)
Format:	Lyophilized

Database Information

KEGG ID :	K04007 \| Matching products
UniProt ID :	P15529 \| Matching products
Gene ID	GeneID 4179 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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