Human CD45 Protein, His Tag

Item number	Size	Manual	SDS	Delivery time	Price
DIM-PME100581.10	10 µg	-	-	7 - 16 business days*	127.00€
DIM-PME100581.50	50 µg	-	-	7 - 16 business days*	459.00€
DIM-PME100581.100	100 µg	-	-	7 - 16 business days*	683.00€

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Recombinant Human CD45 with C-terminal 6×His tag. CD45(Gln26-Lys577) 6×His tag, Protein function:... more

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Product information "Human CD45 Protein, His Tag"

Recombinant Human CD45 with C-terminal 6×His tag. CD45(Gln26-Lys577) 6×His tag, Protein function: Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. [The UniProt Consortium]

Keywords:	B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
Supplier:	DIMA
Supplier-Nr:	PME100581

Properties

Conjugate:	No
Host:	Human cells
Species reactivity:	human
MW:	61.6 kD
Purity:	>95% (SDS-PAGE)
Format:	Lyophilized

Database Information

CAS :	12\| Matching products
KEGG ID :	K06478 \| Matching products
UniProt ID :	P08575 \| Matching products
Gene ID	GeneID 5788 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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