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![Human CCR1 Full-Length Bioactive Membrane Protein](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
G-HDFP075.10 | 10 µg | - | - |
9 - 20 business days* |
1,483.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Chemokine receptor that plays a crucial role in regulating immune cell... more
Product information "Human CCR1 Full-Length Bioactive Membrane Protein"
Protein function: Chemokine receptor that plays a crucial role in regulating immune cell migration, inflammation, and immune responses (PubMed:14991608). Contributes to the inflammatory response by recruiting immune cells, such as monocytes, macrophages, T-cells, and dendritic cells, to sites of inflammation for the clearance of pathogens and the resolution of tissue damage. When activated by its ligands including CCL3, CCL5-9, CCL13-16 and CCL23, triggers a signaling cascade within immune cells, leading to their migration towards the source of the chemokine (PubMed:15905581). For example, mediates neutrophil migration after activation by CCL3 leading to the sequential release of TNF-alpha and leukotriene B4. Mediates also monocyte migration upon CXCL4 binding (PubMed:29930254). Activation by CCL5 results in neuroinflammation through the ERK1/2 signaling pathway. [The UniProt Consortium]
Keywords: | CCR1, CCR-1, CD191, HM145, CMKBR1, CC-CKR-1, RANTES-R, C-C CKR-1, MIP-1alpha-R, LD78 receptor, C-C chemokine receptor type 1, Macrophage inflammatory protein 1-alpha receptor |
Supplier: | Assay Genie |
Supplier-Nr: | HDFP075 |
Properties
Conjugate: | No |
Host: | Human cells |
Species reactivity: | human |
Database Information
KEGG ID : | K04176 | Matching products |
UniProt ID : | P32246 | Matching products |
Gene ID | GeneID 1230 | Matching products |
Handling & Safety
Storage: | -20°C (avoid repeat freezing and thawing cycles) |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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