Human BTLA Protein, mFc-His Tag

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Item number	Size	Manual	SDS	Delivery time	Price
DIM-PME100048.10	10 µg	-	-	7 - 16 business days*	134.00€
DIM-PME100048.50	50 µg	-	-	7 - 16 business days*	518.00€
DIM-PME100048.100	100 µg	-	-	7 - 16 business days*	777.00€

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Recombinant human BTLA protein with C-terminal mouse Fc and 6×His tag. BTLA(Lys31-Ser150)... more

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Product information "Human BTLA Protein, mFc-His Tag"

Recombinant human BTLA protein with C-terminal mouse Fc and 6×His tag. BTLA(Lys31-Ser150) mFc(Pro99-Lys330) 6×His tag, Protein function: Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006, PubMed:15568026, PubMed:18193050). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14 (PubMed:19915044). In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells (PubMed:19915044). [The UniProt Consortium]

Keywords:	BTLA, CD272
Supplier:	DIMA
Supplier-Nr:	PME100048

Properties

Conjugate:	No
Host:	Human cells
Species reactivity:	human
MW:	41.3 kD
Purity:	>95% (SDS-PAGE)
Format:	Lyophilized

Database Information

KEGG ID :	K06707 \| Matching products
UniProt ID :	Q7Z6A9 \| Matching products
Gene ID	GeneID 151888 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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