GCGR (human) full length protein-synthetic nanodisc

Item number Size Datasheet Manual SDS Delivery time Quantity Price
DIM-FLP100085.10 10 µg - -

7 - 16 business days*

1,260.00€
DIM-FLP100085.50 50 µg - -

7 - 16 business days*

6,160.00€
DIM-FLP100085.100 100 µg - -

7 - 16 business days*

11,200.00€
 
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's... more
Product information "GCGR (human) full length protein-synthetic nanodisc"
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing solution by excluding membrane scaffold proteins (MSPs), resulting in a cleaner system with fewer interferences for downstream assays. By disassembling cell membranes into nanoscale disc-shaped structures, our technology enables the purification of membrane proteins to high homogeneity under aqueous conditions. Explore how Synthetic Nanodiscs empower the functional characterization of multi-span transmembrane proteins in their active form, revolutionizing the future of membrane protein research and drug development. Protein function: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system. [The UniProt Consortium]
Keywords: GCGR, GL-R, Glucagon receptor, GGR, GL-R, MVAH, Human GCGR full length protein-synthetic nanodisc
Supplier: DIMA
Supplier-Nr: FLP100085

Properties

Application: Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization
Conjugate: No
Host: Human cells
Species reactivity: human
MW: 54.0 kD
Format: Lyophilized

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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