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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Organism: Homo sapiens (Human). Source: E.Coli. Expression Region: 2-250aa. Protein Length: Full... more
Product information "Galectin-3 protein (LGALS3) (Active), human, recombinant"
Organism: Homo sapiens (Human). Source: E.Coli. Expression Region: 2-250aa. Protein Length: Full Length of Mature Protein. Tag Info: Tag-Free. Target Protein Sequence: ADNFSLHDAL SGSGNPNPQG WPGAWGNQPA GAGGYPGASY PGAYPGQAPP GAYPGQAPPG AYPGAPGAYP GAPAPGVYPG PPSGPGAYPS SGQPSATGAY PATGPYGAPA GPLIVPYNLP LPGGVVPRML ITILGTVKPN ANRIALDFQR GNDVAFHFNP RFNENNRRVI VCNTKLDNNW GREERQSVFP FESGKPFKIQ VLVEPDHFKV AVNDAHLLQY NHRVKKLNEI SKLGISGDID LTSASYTMI. Purity: >98% as determined by SDS-PAGE. Endotoxin: Less than 1.0 EU/µg as determined by LAL method. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to agglutinate human red blood cells is less than 10 µg/ml. Form: Lyophilized powder. Buffer: Lyophilized from a 0.2 µm filtered 1 × PBS, pH 7.4, 3mM DTT. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50%. Customers could use it as reference. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 °C/-80 °C. The shelf life of lyophilized form is 12 months at -20 °C/-80 °C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week. Relevance: Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. {ECO:0000250, ECO:0000269, PubMed:15181153, ECO:0000269, PubMed:19594635, ECO:0000269, PubMed:19616076}. Reference: n/a. Function: Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus
Keywords: | MAC2, L-31, GALBP, Gal-3, CBP 35, Galectin-3, Lectin L-29, Mac-2 antigen, 35 kDa lectin, IgE-binding protein, Laminin-binding protein, Galactose-specific lectin 3, Galactoside-binding protein, Carbohydrate-binding protein 35, Recombinant Human Galectin-3 |
Supplier: | Cusabio |
Supplier-Nr: | AP000481HU |
Properties
Application: | Active protein |
Conjugate: | No |
Species reactivity: | human |
MW: | 26.0 kD |
Purity: | >98% (SDS-PAGE) |
Format: | Lyophilized |
Database Information
KEGG ID : | K06831 | Matching products |
UniProt ID : | P17931 | Matching products |
Gene ID : | GeneID 3958 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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