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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
009-001-R90S | 20 µg | - | - |
6 - 10 business days* |
468.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Recombinant human EPHA8 (565-end) was expressed by baculovirus in Sf9 insect cells using an... more
Product information "EPHA8 protein-GST fusion"
Recombinant human EPHA8 (565-end) was expressed by baculovirus in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >90% by densitometry. Protein function: Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation. With EFNA5 may regulate integrin-mediated cell adhesion and migration on fibronectin substrate but also neurite outgrowth. During development of the nervous system plays also a role in axon guidance. Downstream effectors of the EPHA8 signaling pathway include FYN which promotes cell adhesion upon activation by EPHA8 and the MAP kinases in the stimulation of neurite outgrowth. [The UniProt Consortium]
Keywords: | EEK, EK3, hEK3, EPHA8, EC=2.7.10.1, EPH-like kinase 3, Ephrin type-A receptor 8, EPH- and ELK-related kinase, Tyrosine-protein kinase receptor EEK |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 009-001-R90S |
Properties
Application: | WB |
Conjugate: | No |
Host: | Human |
Database Information
KEGG ID : | K05109 | Matching products |
UniProt ID : | P29322 | Matching products |
Gene ID : | GeneID 2046 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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