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![Dual specificity protein phosphatase 22 (DUSP22), human, recombinant](https://www.biomol.com/media/image/e5/eb/93/CSB-EP865123HU-1_600x600.jpg)
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Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-184aa. Protein Length: Full... more
Product information "Dual specificity protein phosphatase 22 (DUSP22), human, recombinant"
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-184aa. Protein Length: Full Length. Tag Info: N-terminal GST-tagged. Target Protein Sequence: GNGMNKILPG LYIGNFKDAR DAEQLSKNKV THILSVHDSA RPMLEGVKYL CIPAADSPSQ NLTRHFKESI KFIHECRLRG ESCLVHCLAG VSRSVTLVIA YIMTVTDFGW EDALHTVRAG RSCANPNVGF QRQLQEFEKH EVHQYRQWLK EEYGESPLQD AEEAKNILAA PGILKFWAFL RRL. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a. Form: Liquid or Lyophilized powder. Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50%. Customers could use it as reference. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 °C/-80 °C. The shelf life of lyophilized form is 12 months at -20 °C/-80 °C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week. Relevance: Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK). Reference: "Activation of the Jnk signaling pathway by a dual-specificity phosphatase, JSP-1." Shen Y., Luche R., Wei B., Gordon M.L., Diltz C.D., Tonks N.K. Proc. Natl. Acad. Sci. U.S.A. 98:13613-13618(2001). Function: Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) (By similarity).
Keywords: | JSP1, JSP-1, MKP-x, DUSP22, LMW-DSP2, EC=3.1.3.16, EC=3.1.3.48, MAP kinase phosphatase x, JNK-stimulatory phosphatase-1, Dual specificity protein phosphatase 22, Mitogen-activated protein kinase phosphatase x, Recombinant Human Dual specificity protein ph |
Supplier: | Cusabio |
Supplier-Nr: | EP865123HU |
Properties
Application: | Activity not tested |
Conjugate: | No |
Host: | E.coli |
Species reactivity: | human |
MW: | 47.8 kD |
Purity: | >90% (SDS-PAGE) |
Database Information
KEGG ID : | K14165 | Matching products |
UniProt ID : | Q9NRW4 | Matching products |
Gene ID | GeneID 56940 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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