CHRM2 (human) full length protein-synthetic nanodisc

Item number Size Datasheet Manual SDS Delivery time Quantity Price
DIM-FLP100111.10 10 µg - -

7 - 16 business days*

1,260.00€
DIM-FLP100111.50 50 µg - -

7 - 16 business days*

6,160.00€
DIM-FLP100111.100 100 µg - -

7 - 16 business days*

11,200.00€
 
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's... more
Product information "CHRM2 (human) full length protein-synthetic nanodisc"
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing solution by excluding membrane scaffold proteins (MSPs), resulting in a cleaner system with fewer interferences for downstream assays. By disassembling cell membranes into nanoscale disc-shaped structures, our technology enables the purification of membrane proteins to high homogeneity under aqueous conditions. Explore how Synthetic Nanodiscs empower the functional characterization of multi-span transmembrane proteins in their active form, revolutionizing the future of membrane protein research and drug development. Protein function: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3), this then triggers calcium ion release into the cytosol. [The UniProt Consortium]
Keywords: CHRM2, Muscarinic acetylcholine receptor M2, HM2, Human CHRM2 full length protein-synthetic nanodisc
Supplier: DIMA
Supplier-Nr: FLP100111

Properties

Application: Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization
Conjugate: No
Host: Human cells
Species reactivity: human
MW: 51.7 kD
Format: Lyophilized

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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