CHP2 PrEST Antigen

PrEST Antigen CHP2, Gene description: calcineurin like EF-hand protein 2, Antigen sequence: RLHHRFRALDRNKKGYLSRMDLQQIG, Storage: Upon delivery store at -20°C. Avoid repeated freeze/thaw cycles. Protein function: Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus. [The UniProt Consortium] Mouse gene identity: 77% Rat gene identity: 77%