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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ATA-APrEST91364.100 | 100 µl | - | - |
7 - 10 business days* |
247.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: DNA helicase that acts as a chromatin remodeling factor and regulates... more
Product information "CHD8 PrEST Antigen"
Protein function: DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive genes. Involved in both enhancer blocking and epigenetic remodeling at chromatin boundary via its interaction with CTCF. Acts as a suppressor of STAT3 activity by suppressing the LIF-induced STAT3 transcriptional activity. Also acts as a transcription activator via its interaction with ZNF143 by participating in efficient U6 RNA polymerase III transcription. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
Keywords: | CHD-8, HELSNF1, ATP-dependent helicase CHD8, Helicase with SNF2 domain 1, Chromodomain-helicase-DNA-binding protein 8 |
Supplier: | Atlas Antibodies |
Supplier-Nr: | APrEST91364 |
Properties
Application: | Control antigen |
Conjugate: | No |
Host: | E.coli |
Species reactivity: | human |
Database Information
KEGG ID : | K04494 | Matching products |
UniProt ID : | Q9HCK8 | Matching products |
Gene ID : | GeneID 57680 | Matching products |
Handling & Safety
Storage: | -20°C (avoid repeat freezing and thawing cycles) |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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