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Track device being used
![CD273 [PD-L2] (mouse):Fc (mouse) (rec.)](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
CHI-MF-110PDL2-C100 | 100 µg | - | - |
3 - 9 business days* |
429.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The extracellular domain of mouse CD273 [PD-L2] (aa 20-219) is fused to the N-terminus of the Fc... more
Product information "CD273 [PD-L2] (mouse):Fc (mouse) (rec.)"
The extracellular domain of mouse CD273 [PD-L2] (aa 20-219) is fused to the N-terminus of the Fc region of mouse IgG2a. T cells require a signal induced by the engagement of the T cell receptor and a costimulatory signal(s) through distinct T cell surface molecules for optimal T cell activation and tolerance. CD273 (PD-L2) is one of two ligands for programmed death-1 (PD-1, CD279), a member of the CD28 family of immunoreceptors. The other identified ligand is PD-L1. CD273 is broadly expressed and also up regulated in a variety of tumor cell lines. On previously activated T cells, CD273 interaction with PD-1 inhibits TCR mediated proliferation and cytokine production, suggesting an inhibitory role in regulating immune responses. CD273 has a costimulatory function on resting T cells activated with suboptimal TCR signals.
Keywords: | B7dc, PD-L2, CD273, B7-DC, Pdcd1lg2, PD-1 ligand 2, PDCD1 ligand 2, Butyrophilin B7-DC, Programmed death ligand 2, Programmed cell death 1 ligand 2 |
Supplier: | Chimerigen Laboratories |
Supplier-Nr: | MF-110PDL2 |
Properties
Application: | Bioassays |
Conjugate: | No |
Host: | Hamster cells |
Species reactivity: | mouse |
Purity: | >98% |
Format: | Lyophilized |
Database Information
KEGG ID : | K06708 | Matching products |
UniProt ID : | Q9WUL5 | Matching products |
Gene ID | GeneID 58205 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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