B7-H3 Protein (Cynomolgus), His Tag

Description: Recombinant Cynomolgus B7-H3 protein with C-terminal 10-His tag Background: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] Description: Recombinant Cynomolgus B7-H3 protein with C-terminal 10-His tag Molecular Characterization: B7-H3(Leu29-Glu465) 10-His tag Molecular Weight: The protein has a predicted molecular mass of 48.4 kDa after removal of the signal peptide. The apparent molecular mass of cB7-H3-His is approximately 55-100 kDa due to glycosylation. Tag: C-10-His tag