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![APRIL, Soluble, Recombinant, Mouse (ACRP30headless:APRIL, ACRP30headless:CD256, ACRP30headless:TNFS](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
044568.10 | 10 µg | - | - |
3 - 19 business days* |
568.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
APRIL is a cytokine that belongs to the TNF superfamily and binds to TACI and BCMA. It is... more
Product information "APRIL, Soluble, Recombinant, Mouse (ACRP30headless:APRIL, ACRP30headless:CD256, ACRP30headless:TNFS"
APRIL is a cytokine that belongs to the TNF superfamily and binds to TACI and BCMA. It is implicated in the regulation of tumor cell growth, is involved in monocyte/macrophage-mediated immunological processes and functions as an important survival factor for plasmablasts and bone marrow plasma cells. APRIL is a high activity construct in which two trimeric APRIL ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively stimulates proliferation B cell. A basic amino acid sequence (QKQKKQ) close to the N-terminus of APRIL is required for binding to negatively charged sulfated glycosaminoglycan side chains of proteoglycans. Proteoglycans mediate binding of APRIL to tumor cells as well as primary lymphoid cells. Biological Activity: Stimulates B cell proliferation. Sequence: The extracellular domain of mouse APRIL (aa 88-232) is fused at the N-terminus to mouse ACRP30headless (aa 18-110) and a FLAG(R)-tag. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | CD256, April, APRIL, Tnfsf13, A proliferation-inducing ligand, Tumor necrosis factor ligand superfamily member 13 |
Supplier: | United States Biological |
Supplier-Nr: | 044568 |
Properties
Conjugate: | No |
Species reactivity: | mouse |
Format: | Highly Purified |
Database Information
KEGG ID : | K05475 | Matching products |
UniProt ID : | Q9D777 | Matching products |
Gene ID | GeneID 69583 | Matching products |
Handling & Safety
Storage: | vT |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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