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![ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (CD38), partial, human, recombinant](https://www.biomol.com/media/image/de/d0/6f/CSB-EP004929HU2-1_600x600.jpg)
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 46-300aa. Protein Length:... more
Product information "ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (CD38), partial, human, recombinant"
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 46-300aa. Protein Length: Partial. Tag Info: N-terminal GST-tagged. Target Protein Sequence: WRQQWSGPGT TKRFPETVLA RCVKYTEIHP EMRHVDCQSV WDAFKGAFIS KHPCNITEED YQPLMKLGTQ TVPCNKILLW SRIKDLAHQF TQVQRDMFTL EDTLLGYLAD DLTWCGEFNT SKINYQSCPD WRKDCSNNPV SVFWKTVSRR FAEAACDVVH VMLNGSRSKI FDKNSTFGSV EVHNLQPEKV QTLEAWVIHG GREDSRDLCQ DPTIKELESI ISKRNIQFSC KNIYRPDKFL QCVKNPEDSS CTSEI. Purity: Greater than 85% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a. Form: Liquid or Lyophilized powder. Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50%. Customers could use it as reference. Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 °C/-80 °C. The shelf life of lyophilized form is 12 months at -20 °C/-80 °C. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week. Relevance: Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. Reference: "Human gene encoding CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase): organization, nucleotide sequence and alternative splicing." Nata K., Takamura T., Karasawa T., Kumagai T., Hashioka W., Tohgo A., Yonekura H., Takasawa S., Nakamura S., Okamoto H. Gene 186:285-292(1997). Function: nan
Keywords: | T10, CD38, ADPRC 1, EC=3.2.2.6, EC=2.4.99.20, cADPr hydrolase 1, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, 2'-phospho-ADP-ribosyl cyclase, 2'-phospho-cyclic-ADP-ribose transferase, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, Recombinant |
Supplier: | Cusabio |
Supplier-Nr: | EP004929HU2 |
Properties
Application: | Activity not tested |
Conjugate: | No |
Host: | E.coli |
Species reactivity: | human |
MW: | 56.2 kD |
Purity: | >85% (SDS-PAGE) |
Database Information
KEGG ID : | K01242 | Matching products |
UniProt ID : | P28907 | Matching products |
Gene ID | GeneID 952 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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