Suc-Ile-Glu(gamma-pip)-Gly-Arg-pNA (hydrochloride)

Suc-Ile-Glu(gamma-pip)-Gly-Arg-pNA is a colorimetric substrate for Factor Xa. Factor Xa preferentially binds to and cleaves the Ile-Glu(gamma-pip)-Gly-Arg (IE(gamma-pip)GR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of Factor Xa activity.Formal Name: N-(3-carboxy-1-oxopropyl)-L-isoleucyl-5-oxo-5-(1-piperidinyl)-L-norvalylglycyl-N-(4-nitrophenyl)-L-argininamide, monohydrochloride. CAS Number: 1379822-04-4. Synonyms: Succinyl-Ile-Glu(gamma-pip)-Gly-Arg-p-nitroanilide. Molecular Formula: C34H52N10O10 . HCl. Formula Weight: 797.3. Purity: >95% (mixture of tautomers). Formulation: (Request formulation change), A solid. Solubility: DMF: 20mg/mL, DMSO: 3mg/mL, PBS (pH 7.2): 3mg/mL. lambdamax: 272, 315 nm. SMILES: O=C(CC[C@H](NC([C@H]([C@H](CC)C)NC(CCC(O)=O)=O)=O)C(NCC(N[C@@H](CCCNC(N)=N)C(NC1=CC=C([N+]([O-])=O)C=C1)=O)=O)=O)N2CCCCC2.Cl. InChi Code: InChI=1S/C34H52N10O10.ClH/c1-3-21(2)30(42-26(45)14-16-29(48)49)33(52)41-25(13-15-28(47)43-18-5-4-6-19-43)31(50)38-20-27(46)40-24(8-7-17-37-34(35)36)32(51)39-22-9-11-23(12-10-22)44(53)54,/h9-12,21,24-25,30H,3-8,13-20H2,1-2H3,(H,38,50)(H,39,51)(H,40,46)(H,41,52)(H,42,45)(H,48,49)(H4,35,36,37),1H/t21-,24-,25-,30-,/m0./s1. InChi Key: UDIBETPIWZURPW-FTHVRPHQSA-N.