Suc-Ala-Ala-Ala-pNA

Suc-Ala-Ala-Ala-pNA is a colorimetric substrate for elastase. Elastase binds and hydrolyzes Suc-Ala-Ala-Ala-pNA to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of elastase activity.Formal Name: N-(3-carboxy-1-oxopropyl)-L-alanyl-L-alanyl-N-(4-nitrophenyl)-L-alaninamide. CAS Number: 52299-14-6. Synonyms: Elastase Substrate VIII, Suc-AAA-pNA, Suc-AAA-p-nitroanilide, Suc-Ala-Ala-Ala-p-nitroanilide. Molecular Formula: C19H25N5O8. Formula Weight: 451.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 3 mg/ml, DMSO: 5 mg/ml, Ethanol: Slightly soluble, PBS (pH 7.2): 0.3 mg/ml. lambdamax: 222, 315 nm. SMILES: O=C([C@H](C)NC([C@H](C)NC([C@H](C)NC(CCC(O)=O)=O)=O)=O)NC(C=C1)=CC=C1[N+]([O-])=O. InChi Code: InChI=1S/C19H25N5O8/c1-10(20-15(25)8-9-16(26)27)17(28)21-11(2)18(29)22-12(3)19(30)23-13-4-6-14(7-5-13)24(31)32/h4-7,10-12H,8-9H2,1-3H3,(H,20,25)(H,21,28)(H,22,29)(H,23,30)(H,26,27)/t10-,11-,12-/m0/s1. InChi Key: GVUGADOWXGKRAE-SRVKXCTJSA-N.