[Ser4,Ile8]-Oxytocin (trifluoroacetate salt)

[Ser4,Ile8]-Oxytocin is a neuropeptide and analog of oxytocin (Cay-11799). In vivo, [Ser4,Ile8]-oxytocin increases activity of slow-firing oxytocin neurons and triggers the milk ejection reflex in female rats when injected into the third ventricle at a dose of 1 ng. It induces uterine contraction in female rats and prevents penile erection and yawning in male rats. [Ser4,Ile8]-Oxytocin also decreases blood glucose, glucose intolerance, and hyperinsulinemia without affecting body weight in mice with high-fat diet-induced type 2 diabetes.Formal Name: 4-L-serine-8-L-isoleucine-oxytocin, trifluoroacetate salt. Synonyms: Isotocin. Molecular Formula: C41H63N11O12S2 . XCF3COOH. Formula Weight: 966.1. Purity: >95%. Formulation: (Request formulation change), A lyophilized powder. Solubility: Water: 1 mg/ml. SMILES: NC(CNC([C@@]([C@H](CC)C)([H])NC([C@@H]1CCCN1C([C@@H](N2)CSSC[C@H](N[H])C(N[C@H](C(N[C@]([C@H](CC)C)([H])C(N[C@@H](CO)C(N[C@@H](CC(N)=O)C2=O)=O)=O)=O)CC3=CC=C(O)C=C3)=O)=O)=O)=O)=O.FC(F)(C(O)=O)F. InChi Code: InChI=1S/C41H63N11O12S2.C2HF3O2/c1-5-20(3)32(39(62)45-16-31(44)56)51-38(61)29-8-7-13-52(29)41(64)28-19-66-65-18-24(42)34(57)46-25(14-22-9-11-23(54)12-10-22)36(59)50-33(21(4)6-2)40(63)48-27(17-53)37(60)47-26(15-30(43)55)35(58)49-28,3-2(4,5)1(6)7/h9-12,20-21,24-29,32-33,53-54H,5-8,13-19,42H2,1-4H3,(H2,43,55)(H2,44,56)(H,45,62)(H,46,57)(H,47,60)(H,48,63)(H,49,58)(H,50,59)(H,51,61),(H,6,7)/t20-,21-,24-,25-,26-,27-,28-,29-,32-,33-,/m0./s1. InChi Key: HZGFKIAVKSCMJC-XTYGDVRLSA-N.