Relamorelin

Description: Relamorelin (RM-131), a selective and potent growth hormone-releasing peptide/growth hormone secretagogue receptor (GHSR) agonist, is a potent growth hormone-releasing peptide mimetic with a high affinity for the GHS-1a receptor Relamorelin is a centrally permeable pentapeptide that increases growth hormone levels and accelerates gastric emptying and has potential for studying malignant disease. Target: GHSR. Smiles: C([C@@H](NC([C@@H](CC=1C=2C(SC1)=CC=CC2)NC(=O)C3CCNCC3)=O)C(N[C@H](C(NC4(C(N)=O)CCNCC4)=O)CC5=CC=CC=C5)=O)C=6C=7C(NC6)=CC=CC7. References: Fischer K, et, al. The Pentapeptide RM-131 Promotes Food Intake and Adiposity in Wildtype Mice but Not in Mice Lacking the Ghrelin Receptor. Front Nutr. 2015 Jan 12,1:31.