Mca-PLGL-Dpa-AR-NH2 (trifluoroacetate salt)

Mca-PLGL-Dpa-AR-NH2 is a fluorogenic substrate for matrix metalloproteinase-2 (MMP-2) and MMP-7. Upon cleavage by MMP-2 or MMP-7, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify MMP activity. Mca displays excitation/emission maxima of 328/420 nm, respectively.Formal Name: (S)-N-((6S,9S,12S,15S,21S)-1-amino-12-(aminomethyl)-6-carbamoyl-1-imino-15-isobutyl-9,23-dimethyl-8,11,14,17,20-pentaoxo-2,7,10,13,16,19-hexaazatetracosan-21-yl)-1-(2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetyl)pyrrolidine-2-carboxamide, trifluoroacetate salt. Synonyms: Matrix Metalloproteinase-2/Matrix Metalloproteinase-7 Fluorogenic Substrate, Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2, MMP-2/MMP-7 Fluorogenic Substrate. Molecular Formula: C43H66N12O11 . XCF3COOH. Formula Weight: 927.1. Purity: >95%. Formulation: (Request formulation change), A lyophilized powder. Solubility: Water: 1 mg/ml. SMILES: COC1=CC=C(C(CC(N2[C@H](C(N[C@@H](CC(C)C)C(NCC(N[C@H](C(N[C@@H](CN)C(N[C@@H](C)C(N[C@H](C(N)=O)CCCNC(N)=N)=O)=O)=O)CC(C)C)=O)=O)=O)CCC2)=O)=CC(O3)=O)C3=C1.FC(F)(C(O)=O)F. InChi Code: InChI=1S/C43H66N12O11/c1-22(2)15-29(53-42(64)32-10-8-14-55(32)35(57)17-25-18-36(58)66-33-19-26(65-6)11-12-27(25)33)39(61)49-21-34(56)51-30(16-23(3)4)40(62)54-31(20-44)41(63)50-24(5)38(60)52-28(37(45)59)9-7-13-48-43(46)47/h11-12,18-19,22-24,28-32H,7-10,13-17,20-21,44H2,1-6H3,(H2,45,59)(H,49,61)(H,50,63)(H,51,56)(H,52,60)(H,53,64)(H,54,62)(H4,46,47,48)/t24-,28-,29-,30-,31-,32-/m0/s1. InChi Key: GNGRCYXAOSUGRN-KNIQQNQGSA-N.