Linaclotide
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Linaclotide, developed for the treatment of constipation-predominant irritable bowel... more
Product information "Linaclotide"
Description: Linaclotide, developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation, is a potent and selective guanylate cyclase C agonist. Target: Guanylate cyclase. Smiles: C[C@@H](O)C1NC(=O)[C@@H]2CSSC[C@@H]3NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CSSC[C@H](NC(=O)CNC1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC3=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N2. References: Bryant AP, et al. Linaclotide is a potent and selective guanylate cyclase C agonist that elicits pharmacological effects locally in the gastrointestinal tract. Life Sci. 2010 May 8,86(19-20):760-5.
| Supplier: | TargetMol |
| Supplier-Nr: | T11852 |
Properties
| Application: | Targets heat-stable enterotoxin receptor [EC:4.6.1.2] (GUCY2C) |
| Conjugate: | No |
| MW: | 1526.74 D |
| Formula: | C59H79N15O21S6 |
Database Information
| CAS : | 851199-59-2| Matching products |
| KEGG ID : | K12320 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302 |
| P Phrases: | P264, P270, P330, P301+P310, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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