Laminin (925-933)

Laminin (925-933) is a peptide fragment corresponding to the laminin beta1 chain. It binds to the laminin receptor when used at a concentration of 1 mg/ml. Laminin (925-933) stimulates the attachment of HT-1080 and CHO cells to culture plates when used at concentrations of 100 and 300 µg/ml. It induces chemotaxis of, as well as inhibits chemotaxis induced by full-length laminin, but not fibronectin, in B16/F10 murine melanoma cells. Laminin (925-933) conjugated to an agarose hydrogel backbone enhances neurite outgrowth in isolated chick embryo dorsal root ganglia and PC12 cells.Formal Name: L-cysteinyl-L-alpha-aspartyl-L-prolylglycyl-L-tyrosyl-L-isoleucylglycyl-L-seryl-L-arginine. CAS Number: 110590-60-8. Synonyms: CDPGYIGSR, Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg. Molecular Formula: C40H62N12O14S. Formula Weight: 967.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: O=C([C@H]1N(C([C@H](CC(O)=O)NC([C@@H](N)CS)=O)=O)CCC1)NCC(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(NCC(N[C@@H](CO)C(NC(CCCNC(N)=N)C(O)=O)=O)=O)=O)[C@@H](C)CC)=O)=O. InChi Code: InChI=1S/C40H62N12O14S/c1-3-20(2)32(37(63)46-17-30(56)48-27(18-53)35(61)49-24(39(65)66)6-4-12-44-40(42)43)51-34(60)25(14-21-8-10-22(54)11-9-21)47-29(55)16-45-36(62)28-7-5-13-52(28)38(64)26(15-31(57)58)50-33(59)23(41)19-67/h8-11,20,23-28,32,53-54,67H,3-7,12-19,41H2,1-2H3,(H,45,62)(H,46,63)(H,47,55)(H,48,56)(H,49,61)(H,50,59)(H,51,60)(H,57,58)(H,65,66)(H4,42,43,44)/t20-,23-,24?,25-,26-,27-,28-,32-/m0/s1. InChi Key: NGBBIWFVAWMQKZ-RMYNKKRNSA-N.