Histone H3K9Me3 (3-17) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)

Histone H3K9Me3 (3-17) is an N-terminal peptide fragment of histone H3 that corresponds to amino acid residues 4-18 of the human histone H3 sequence. Trimethylation of histone H3 at lysine 9 is associated with gene repression, prevents transcription factor binding, and is a target of the heterochromatin protein 1 (HP1) family proteins CBX1, CBX3, and CBX5. It is recognized by the plant homeodomain fingers of chromodomain helicase DNA binding protein 4 (CHD4), a member of the NuRD deacetylase complex that is upregulated in a variety of cancers and implicated in the DNA damage response.Formal Name: L-threonyl-L-lysyl-L-glutaminyl-L-threonyl-L-alanyl-L-arginyl-6-(trimethylammonio)-L-norleucyl-L-seryl-L-threonylglycylglycyl-L-lysyl-L-alanyl-L-prolyl-L-arginine, trifluoroacetate salt. Synonyms: H-Thr-Lys-Gln-Thr-Ala-Arg-Lys(Me3)-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-OH, H3K9me3, Histone H3 (3-17) (Lys9me3), [Lys(Me3)9]-Histone H3 (3-17), TKQTAR-K(Me3)-STGGKAPR. Molecular Formula: C68H125N25O21 . XCF3COOH. Formula Weight: 1628.9. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: 1 mg/ml. SMILES: C[N+](C)(C)CCCC[C@H](NC([C@@H](NC([C@H](C)NC([C@@]([H])(NC([C@@H](NC([C@@H](NC([C@@]([H])(N)[C@H](O)C)=O)CCCCN)=O)CCC(N)=O)=O)[C@H](O)C)=O)=O)CCCNC(N)=N)=O)C(N[C@H](C(N[C@]([H])(C(NCC(NCC(N[C@H](C(N[C@@H](C)C(N1CCC[C@H]1C(N[C@H](C([O-])=O)CCCNC(N)=N)=O)=O)=O)CCCCN)=O)=O)=O)[C@H](O)C)=O)CO)=O.O=C(O)C(F)(F)F. InChi Code: InChI=1S/C68H125N25O21.C2HF3O2/c1-35(81-64(111)53(39(5)97)91-59(106)44(24-25-48(71)98)86-56(103)42(19-10-13-27-70)87-62(109)51(72)37(3)95)54(101)84-43(21-15-28-77-67(73)74)57(104)85-41(20-11-14-31-93(6,7)8)58(105)89-46(34-94)60(107)90-52(38(4)96)63(110)80-32-49(99)79-33-50(100)83-40(18-9-12-26-69)55(102)82-36(2)65(112)92-30-17-23-47(92)61(108)88-45(66(113)114)22-16-29-78-68(75)76,3-2(4,5)1(6)7/h35-47,51-53,94-97H,9-34,69-70,72H2,1-8H3,(H23-,71,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88,89,90,91,98,99,100,101,102,103,104,105,106,107,108,109,110,111,113,114),(H,6,7)/t35-,36-,37+,38+,39+,40-,41-,42-,43-,44-,45-,46-,47-,51-,52-,53-,/m0./s1. InChi Key: QKOTUXPXCRYHIO-DFZJYLPLSA-N.